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Analisis Survival Menggunakan Stata

Analisis Survival Menggunakan Stata

Analisis survival digunakan apabila variabel dependennya berupa data waktu
dan kita lebih mementingkan kapan terjadinya suatu kejadian (event) dari pada apakah
kejadian itu terjadi atau tidak
Misalkan kita akan meneliti dua jenis obat terhadap lama tahannya suatu pasien kanker
 
Masukkan datanya
Statistic > survival analysis > set up & utilities > declare data to be survival-time data
Akan keluar dialog box berikut:
 
Pada time variable: pilih variabel waktu
Pada failure variable: pilih status
Pada failure valued: ketik 1
Klik Ok
Berikut outputnya:
 
Pengecekan asumsi proporsional hazard
  1. Metode kapplan meier
Statistics > survival analysis > Graph > kapplan meier survivor function
 
 
Cek list make separate calculation by group:
Pada grouping variables: pilih obat
Klik OK
 
Terlihat asumsi terpenuhi karena garisnya tidak memotong
  1. Metode ln –ln survival
Statistics > survival analysis > regresiion model > graphically assess proprtional hazard assumption
 
 
Pada independen variable: pilih variabel obat
Klik OK
Berikut hasilnya:
 
terlihat garisnya tidak berpotongan berarti asumsinya terpenuhi
3. global test
Statistics > survival analysis > regresiion model > cox proporsional hazard model
 
Pada independen variabel: klik i.obat
Klik ok
 
Terlihat nilai hazard rasio sebsar 4.58
Statistics > survival analysis > regresiion model > test proporsional hazard assumption
 

Klik Ok

 

Model persamaan
Statistics > survival analysis > regresiion model > cox proporsional hazard model

 

Pada independen variables: pilih obat
Klik menu reporting
 
Cek list, report coeddicient, not hazar ratios
Klik OK
 
Sehingga persamaan yang dihasilaka:
Hazard function: H(t)=H0 (t) e1.523105 *jenis_obat
Survival function: S(t)=S0 (t) e1.523105 *jenis_obat
 
Menhasilkan hazard baseline
xi:stcox i.obat, basechazard(h0)
tabulate waktu, summarize(h0) nostandard nofreq noobs
 
 
Menhasilkan survival baseline
xi:stcox i.obat, basesurv(s0)
tabulate waktu, summarize(s0) nostandard nofreq noobs
 

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